Which of the following best describes the grade of acne known for nodules and cysts?

The grade of acne characterized by the presence of nodules and cysts is classified as Grade IV. This level of acne is also known as cystic acne, which is the most severe form. It typically involves deep-seated, painful lesions that can lead to significant scarring and are often more challenging to treat.

Nodules are large, solid lesions that form deep in the skin, while cysts are pus-filled, round lesions that can be soft and inflamed. At this stage, the acne is not only more extensive and severe but also may require more aggressive treatments such as prescription medications or interventions by a dermatologist.

In contrast, the other grades of acne represent less severe forms. Grade I features minor comedonal acne (blackheads and whiteheads), Grade II includes more inflamed papules and a few pustules, and Grade III presents with a more significant amount of inflamed lesions but does not typically involve cysts or nodules. This clarity on the severity of each grade emphasizes why Grade IV is specifically associated with nodules and cysts.